游静
职称：博士/教授/博导
单位：暨南大学环境与气候学院
电话：020-8522-6326
邮箱：youjing@jnu.edu.cn
网站：http://yourlab.com.cn/PicDetail.aspx?ID=72
生态毒理学、水生态风险评估与管理
游静，暨南大学环境与气候学院教授，主要从事生态毒理学及水生态风险评价与管理研究。1996年本科毕业于长春地质学院，2000年在中国科学院兰州化学物理研究所获分析化学博士学位后赴美，在南伊利诺伊大学从事分析化学与水生毒理学的研究，2007年任美国中密苏里大学分析化学Tenure-track助理教授。2009年通过中科院“百人计划”回国工作，2012年获国家基金委地学部“优秀青年基金”资助，2016年入选广东省特支计划科技创新领军人才。
主要从事水生毒理学与沉积物生态风险评价研究，以污染物的生物可利用性与毒性的关联机制为核心问题，系统研究现用农药等有机污染物的环境行为、毒性特征和毒代动力学过程，并通过有害结局路径和大数据分析构建复合污染条件下的毒性识别技术体系，为水生态风险评价方法及水环境基准的研究提供科学基础和技术支撑（http://yourlab.com.cn/PicDetail.aspx?ID=72）。重点研究以效应为导向的新污染物筛查和评价方法学，系统探讨了复合污染环境中有机污染物的生物有效性、迁移转化和毒性成因，提出事件驱动分类法（EDT）的概念，结合效应导向分析（EDA）开展关键致毒物识别，发展了集成有害结局路径、大数据分析、非靶标筛查的复合污染毒性识别及新污染物筛查技术，构建基于生命周期理念的化学品双向管控模式。在SCI杂志上发表论文180余篇（第一/通讯作者论文100余篇），SCI论文他引4000余次。曾担任国际环境毒理与化学协会（SETAC）亚太分会主席、《Integrated Environmental Assessment and Management》、《应用生态学报》编委，目前担任中国环境科学学会沉积物环境专业委员会委员，以及《Environmental Toxicology and Chemistry》、《Review of Environmental Contamination and Toxicology》、《生态毒理学报》、《分析测试技术与仪器》副主编，以及《Science of the Total Environment》和《环境化学》编委。2011年获SETAC与英国皇家化学协会联合颁发的“SETAC/RSC”青年科学家奖，培养的学生获得包括2014年度中国科学院院长特别奖、2015年度中国科学院优秀博士学位论文、2023全国大学生创新创业年会优秀论文等多项奖励。
1. 效应导向非目标筛查与识别；
2. 有机污染物生物可利用性与毒性；
3. 新污染物的生态健康效应和风险评价
4. 污染物的复合毒性效应与分子机制；
5. 新污染物的环境分布、行为和生态风险
《环境问题》（广东省一流课程）
《环境化学》
《生态风险评估》
近五年第一/通讯作者论文（2019-）
1. Wang D.-L., Ding Q., Zhong Y.-H., Han X.-F., Fu L., Yu J., Li K.-T. You J.* Effects of erythromycin on Nereis succinea and the intestinal microbiome across different salinity levels, Environmental Science & Technology, 2024, 58(6), 2662–2671
2. Xiong J.-J., Li H.-Z., Ma X., Tan B.-X., Gong Y.-T., Xie D., Wang L., Yi H., You J*. Tracing the attenuation of fipronil and its transformation products from a rice paddy field to receiving rivers using polar organic chemical integrative samplers. Science of the Total Environment, 2023, 904, 166824
3. Cheng F., Huang J.-H., Li H.-Z.*, Escher B.I., Tong Y.-J., König M., Wang D.-L, Wu F., Yu Z.-Q., Brooks B.W., You J.*, Text mining-based suspect screening for aquatic risk assessment in the big data era: Event-driven taxonomy links chemical exposures and hazards, Environmental Science & Technology Letters, 2023, 10(11), 1004–1010
4. Wu F.*, Keyan Chen, Cheng F, You J.* Life cycle thinking supports 21st century new pollutant and chemical management, Integrated Environmental Assessment and Management, 2023, 19(4), 859-860
5. Wang D.L., Zhong Y.H., Ding Q., Han X.F., Chen K., Pan B., You J*. Distinct effects of nano-polystyrene, erythromycin and their mixtures on composition and metabolic profile of intestinal microbiota in Nereis succinea. Environ. Sci. Nano. 2023, 10, 2053–2065
6. Wu F., Zhou Z.-M., Zhang S.-Q., Cheng F., Tong Y.-J., Li L., Zhang B., Zeng X.-Y., Li H.-Z., Wang D.-L., Yu Z.-Q., You J.* Toxicity identification evaluation for hydraulic fracturing flowback and produced water during shale gas exploitation in China: Evidence from tissue residues and gene expression. Water Research, 2023, 241, 120170
7. Cheng F, Zhou Z. M., Wu F., Li H. Z., Yu Z.Q., Zeng X.Y., You J*. Data-driven endpoint selection in data-poor scenarios: Bioassay design for shale gas flowback and produced waters. Environmental Science & Technology Letters, 2022. 9(12), 1074–1080
8. Zhang L., Brooks B.W.*, Liu F., Zhou Z.-M., Li H.-Z., You J.* Human apparent volume of distribution predicts bioaccumulation of ionizable organic chemicals in zebrafish embryos. Environmental Science & Technology, 2022, 56(16), 11547–11558
9. Zhou Z.M., Bai Y.F., Su T.H., Zhang D.N., Wang Z., Begnaud F., Gimeno S., You J.*, Investigations on the fish acute toxicity of fragrance ingredients involving Chinese fish species and zebrafish embryos, Environmental Toxicology and Chemistry. 2022, 41(9), 2305–2317
10. Wang D.-L., Ning Q., Deng Z.-Q., Zhang M., You J.* Role of environmental stresses in elevating resistance mutations in bacteria: Phenomena and mechanisms, Environmental Pollution. 2022, 307,119603
11. Wu F., Crandon L., Li L., Cao Y.-Y., Hicks A., Zeng E.Y., You J*. Environmental hotspots and greenhouse gas reduction potential for different lithium-ion battery recovery strategies, Journal of Cleaner Production, 2022, 339, 130697
12. Huang Z.B., Li H.Z., Xiong J.J., You J.* Target and suspect screening of urinary biomarkers for current-use pesticides: Application of a simple extraction method. Environmental Toxicology Chemistry, 2022, 41(1), 73–80
13. Xie P.-H., Yan Q.-K., Xiong J.-J., Li H.-Z., Ma X., You J.*, Point or non-point source: Toxicity evaluation using m-POCIS and zebrafish embryos in municipal sewage treatment plants and urban waterway, Environmental Pollution, 2022, 292, 118307
14. Cheng F., Li H.Z., Brooks B.W., You J.*, Signposts for aquatic toxicity evaluation in China: Text mining using event-driven taxonomy within and among regions, Environmental Science & Technology, 2021, 55(13), 8977-8986
15. Xiong J.J., Tan B.X., Ma X., Li H. Z., You J.*, Tracing neonicotinoid insecticides and their transformation products from paddy field to receiving waters using polar organic chemical integrative samplers. Journal of Hazardous Materials, 2021, 413, 125421
16. Li H.-Z., Zhang Q.-J., Su H., You J.*, Wang W.-X. High tolerance and delayed responses of Daphnia magna to neonicotinoid insecticide imidacloprid: Toxicokinetic and toxicodynamic modeling. Environmental Science & Technology, 2021, 55, 458−467
17. Cheng F., Li H.-Z., Brooks B.W., You J.* Retrospective risk assessment of chemical mixtures in the big data era: An alternative classification strategy to integrate chemical and toxicological data. Environmental Science & Technology, 2020. 54(10), 5925–5927
18. Wang D.-L., Ren J.-B., Tan Z.-Y., You J.* Gut microbial profiles in Nereis succinea and their contribution to the degradation of organic pollutants. Environmental Science & Technology, 2020. 54(10), 6235–6243
19. Xiong J.-J., Li H.-Z., Ma X., Tan B.-X., You J.* A new configuration of polar organic chemical integrative sampler with nylon membranes to monitor emerging organophosphate ester contaminants in urban surface water, Ecotoxicology and Environmental Safety. 2020. 202, 110891
20. Wang S.-H., Lao W.-J.*, Li, H.-Z., You J.* Measuring bioconcentration factors of sediment-associated fipronil in Lumbriculus variegatus using passive sampling techniques. Journal of Hazardous Materials, 2020, 393, 122420
21. Wang D.-L., Ning Q., Dong J.-Y., Brooks B.W, You J.* Predicting mixture toxicity and antibiotic resistance of fluoroquinolones and their photodegradation products in Escherichia coli. Environmental Pollution, 2020. 262, 114275
22. Wang Z., Berninger J.P., You J.*, Brooks B.W., One uncertainty factor does not fit all: Identifying mode of action and species specific acute to chronic ratios for aquatic life. Environmental Pollution 2020. 262, 114262
23. Huang Z.-B, Li, H.-Z., Wei Y.-L., Xiong J.-J., You J.* Distribution and ecological risk of neonicotinoid insecticides in sediment in South China: Impact of regional characteristics and chemical properties. Science of the Total Environment. 2020. 714, 136878
24. Tan B.-X., Xiong J.-J., Li, H.-Z., You J.* Simultaneous analysis of current-use pesticides and their transformation products in water using mixture-sorbent solid phase extraction and HPLC-MS/MS. Journal of Separation Science, 2020 43(12), 2409–2418
25. Cheng F., Li H.-Z., Ma H.-M., Wu F.-C., Fu Z.-Y., You J.* Identifying bioaccessible suspect toxicants in sediment using adverse outcome pathway directed analysis, Journal of Hazardous Materials, 2020. 389, 121853
26. Wei F.-H., Su T.-H., Wang D.-L., Li H.-Z., You J.* Transcriptomic analysis reveals common pathways and biomarkers associated with oxidative damage caused by mitochondrial toxicants in Chironomus dilutus. Chemosphere. 2020. 254, 126746
27. Wei F.-H., Wang D.-L., Li H.-Z., Xia P., Ran Y., You J.* Toxicogenomics provides insights to toxicity pathways of neonicotinoid to aquatic insect, Chironomus dilutus. Environmental Pollution, 2020. 260, 114011
28. Wang S.-H., Li H.-Z., You J.* Enantioselective degradation and bioaccumulation of sediment-associated fipronil in Lumbriculus variegatus: Toxicokinetic analysis. Science of the Total Environment, 2019, 672, 335–341
29. Ma X., Li H.-Z., Xiong J.J., Mehler W.T., You J.* Developmental toxicity of a neonicotinoid insecticide, acetamiprid to zebrafish embryos, Journal of Agricultural and Food Chemistry, 2019, 67(9), 2429–2436
30. Wang Z., Brooks B.W., Zeng E.Y., You J.* Comparative mammalian hazards of neonicotinoid insecticides among exposure durations, Environmental International, 2019, 125, 9–24
31. Xiong J.J., Wang Z., Ma X., Li, H.-Z., You J.* Occurrence and risk of neonicotinoid insecticides in surface water in a rapidly developing region: Application of polar organic chemical integrative samplers, Science Total of Environment, 2019, 648, 1305–1312
32. Li H.-Z., Yi X.-Y., Cheng F., Tong Y.-J., Mehler W.T., You J.* Identifying organic toxicants in sediment using effect-directed analysis: a combination of bioaccessibility-based extraction and high-throughput midge toxicity testing, Environmental Science & Technology, 2019, 53, 996–1003
2024.01-2027.12 41977343 国家自然科学基金面上项目，基于生物效应的非目标筛查策略：深度学习用于水环境中新污染物识别, 执行中（项目负责人）
2023.01-2025.12 2023A515011396 广东省自然科学基金面上项目，基于水环境原位暴露的生物效应导向分析方法构建及其在新污染物筛查中的应用, 执行中（项目负责人）
2021.04-2024.03202103000046 广州市民生项目，基于原位效应和数据挖掘的广州市水污染监测及防控技术集成, 执行中（项目负责人）
2021.01-2023.12 2020KCXTD005 广东省普通高校创新团队项目（自然科学），水生态风险评价与管理 ，结题（负责人：游静）
2020.01-2023.12 U1901220，国家自然科学基金委-广东省联合基金重点项目，大湾区河口典型有机污染特征及基于多证据链的生态效应，结题（项目负责人）
2020.01-2023.122019YFC1805501，国家重点研发计划项目子课题，页岩气开采场地特征污染物筛查与污染防控-页岩气开采过程中特征污染物的识别与筛选，结题（子课题负责人）
2020.01-2023.12 41977343 国家自然科学基金面上项目，基于有害结局路径导向分析的城市水体沉积物毒性鉴别评价，结题中（项目负责人）
2019.01-2021.12比利时Firmenich（法国Oreal公司）合作项目，Investigations on alternatives to fish acute toxicity tests, involving the Chinese fish species for China notifications，结题（项目负责人）
2018.01-2021.12 41773101 国家自然科学基金面上项目，农业区水-沉积物体系中常见杀虫剂的迁移降解行为及其对沉积物毒性的影响机制，结题（项目负责人）
2017.01-2020.12 2017ZX07301-005-002 国家重大科技项目水体污染控制与治理科技重大专项子课题，流域水环境风险管理技术集成-流域水环境复合污染生态风险评估技术体，结题（子课题负责人）
2017.01-2019.12 2017A020216002 广东省省级科技计划项目，结合水体被动采样的效应导向分析方法的建立与应用，结题（项目负责人）
2016.07-2019.06 2015TX01Z168 广东省科技创新领军人才项目，环境监测与环境风险评价技术，结题（项目负责人）
2015.01-2018.12 41473106，国家自然科学基金面上项目，被动采样在珠三角典型城市水体沉积物毒性评价中的应用：常见农药体内代谢分配的影响，结题（项目负责人）
2013.01-2016.12 41273120，国家自然科学基金面上项目，珠江广州段水体沉积物生态毒性的鉴别与评价，结题（项目负责人）
2013.01-2015.12 41222024，国家自然科学基金优秀青年基金项目，环境地球化学，结题（项目负责人）
2010.01-2012.12 40971263，国家自然科学基金面上项目，沉积物中超级吸附剂
超级吸附剂及生物扰动对疏水性有机污染物的生物有效性和生物积累的影响，结题（课题负责人）
环境污染与健康团队