游静
职称：博士/教授/博导
单位：暨南大学环境学院
电话：020-8522-6326
邮箱：youjing@jnu.edu.cn
网站：http://yourlab.com.cn/PicDetail.aspx?ID=72
水体沉积物生态风险评价
博士生导师、获选多项国家和省级重点人才项目和奖项。1996年毕业于长春地质学院，2000年在中科院兰州化学物理研究所获分析化学博士学位后赴美，在南伊利诺伊大学从事分析化学与水生毒理学研究，2007年任美国中密苏里大学环境分析化学Tenure-track助理教授。2009年全职回国，在广州地球化学研究所工作（研究员），2016年入职暨南大学。研究团队（水生态风险评价与管理）于2020年获批广东省教育厅普通高校创新团队。国际环境毒理与化学协会（SETAC）亚太分会常务理事会前任主席、SETAC全球理事会常务理事、中国环境科学学会沉积物环境专业委员会委员。担任国际环境毒理学主流刊物 Environmental Toxicology and Chemistry 副主编、Science Total of Environment 和Integrated Environmental Assessment and Management 编委、《分析测试技术与仪器》副主编、《环境化学》和《应用生态学报》编委。
主要从事水生毒理学与沉积物生态风险评价研究，以污染物的生物可利用性与毒性的关联机制为核心问题，系统研究现用农药等有机污染物的环境行为、毒性特征和毒代动力学过程，并通过有害结局路径和大数据分析构建复合污染条件下的毒性识别技术体系，为水生态风险评价方法及水环境基准的研究提供科学基础和技术支撑（http://yourlab.com.cn/PicDetail.aspx?ID=72）。迄今在SCI杂志上发表论文138篇（其中第一/通讯作者论文85篇），SCI论文他引2000余次，h指数为31。2011年获SETAC与英国皇家化学协会联合颁发的“SETAC/RSC”青年科学家奖，2013年度中国科学院大学-BHPB导师科研奖、2014年度中国科学院优秀导师奖、2014年度中科院广州教育基地优秀研究生导师奖、2015年度中国科学院优秀研究生指导教师奖。培养的研究生获得包括2014年度中国科学院院长特别奖、2015年度中国科学院优秀博士学位论文等多项奖励。
1.沉积物的生态风险评价方法；
2.污染物生物可利用性对毒性的影响机制；
3.生物效应导向的致毒污染物识别；
4.污染物的复合毒性效应与分子机制；
5.农药的环境分布、行为和生态风险。
生态风险评价（研究生）
环境问题（本科生）
环境化学（本科生）
2017-2021
1. Li H.-Z., Zhang Q.-J., Su H., You J.*, Wang W.-X. High tolerance and delayed responses of Daphnia magna to neonicotinoid insecticide imidacloprid: Toxicokinetic and toxicodynamic modeling. Environmental Science & Technology, 2021. 55, 458−467
2. Xiong J.J., Tan B.X., Ma X., Li H.Z., You J.*, Tracing neonicotinoid insecticides and their transformation products from paddy field to receiving waters using polar organic chemical integrative samplers. Journal of Hazardous Materials, 2021. 413, 125421
3. Wei F.-H., Wang D.-L.*, Li H.-Z., You J. Joint toxicity of imidacloprid and azoxystrobin to Chironomus dilutus at organism, cell, and gene levels. Aquatic Toxicology. 2021. 233, 105783
4. Liang Y., Hu L., Li J., Liu F., Jones K.C., Li D., Liu J., Chen D., You J., Yu Z., Zhang G., Dong G., Ma H.* Short-term personal PM2.5 exposure and change in DNA methylation of imprinted genes: Panel study of healthy young adults in Guangzhou city, China. Environmental Pollution, 2021. 275, 116601
5. Xiong J.-J., Li H.-Z., Ma X., Tan B.-X., You J.* A new configuration of polar organic chemical integrative sampler with nylon membranes to monitor emerging organophosphate ester contaminants in urban surface water, Ecotoxicology and Environmental Safety. 2020. 202, 110891
6. Cheng F., Li H.-Z., Brooks B.W., You J.* Retrospective risk assessment of chemical mixtures in the big data era: An alternative classification strategy to integrate chemical and toxicological data. Environmental Science & Technology, 2020. 54, 5925-5927.
7. Wang D.-L., Ren J.-B., Tan Z.-Y., You J.* Gut microbial profiles in Nereis succinea and their contribution to the degradation of organic pollutants. Environmental Science & Technology, 2020. 54, 6235-6243.
8. Wang S.-H., Lao W.-J.*, Li, H.-Z., You J.* Measuring bioconcentration factors of sediment-associated fipronil in Lumbriculus variegatus using passive sampling techniques. Journal of Hazardous Materials, 2020, 393, 122420.
9. Cheng F., Li H.-Z., Ma H.-M., Wu F.-C., Fu Z.-Y., You J.* Identifying bioaccessible suspect toxicants in sediment using adverse outcome pathway directed analysis, Journal of Hazardous Materials, 2020. 389, 121853.
10. Wei F.-H., Su T.-H., Wang D.-L., Li H.-Z., You J.* Transcriptomic analysis reveals common pathways and biomarkers associated with oxidative damage caused by mitochondrial toxicants in Chironomus dilutus. Chemosphere. 2020. 254, 126746.
11. Wang D.-L., Ning Q., Dong J.-Y., Brooks B.W, You J.* Predicting mixture toxicity and antibiotic resistance of fluoroquinolones and their photodegradation products in Escherichia coli. Environmental Pollution, 2020. 262, 114275.
12. Wang Z., Berninger J.P., You J.* Brooks B.W., One uncertainty factor does not fit all: Identifying mode of action and species specific acute to chronic ratios for aquatic life. Environmental Pollution 2020. 262, 114262.
13. Wei F.-H., Wang D.-L., Li H.-Z., Xia P., Ran Y., You J.* Toxicogenomics provides insights to toxicity pathways of neonicotinoid to aquatic insect, Chironomus dilutus. Environmental Pollution, 2020. 260, 114011.
14. Huang Z.-B, Li, H.-Z., Wei Y.-L., Xiong J.-J., You J.* Distribution and ecological risk of neonicotinoid insecticides in sediment in South China: Impact of regional characteristics and chemical properties. Science of the Total Environment. 2020. 714, 136878.
15. Tan B.-X., Xiong J.-J., Li, H.-Z., You J.* Simultaneous analysis of current-use pesticides and their transformation products in water using mixture-sorbent solid phase extraction and HPLC-MS/MS. Journal of Separation Science, 2020, 43, 2409-2418
16. Brooks B.W.*, Sabo-Attwood T., Choi K., Kim S., Kostal J., LaLone C.A., Langan L.M., Margiotta-Casaluci L., You J., Zhang X.-W., Toxicology advances for 21st century chemical pollution, One Earth, 2020, 2, 312-316
17. Zhang L.-J.1, Yang J.H.1, Li H.-Z.*, You J., Chatterjee N., Zhang X.-W.* Development of the transcriptome for a sediment ecotoxicological model species, Chironomus dilutus. Chemosphere, 2020, 244, 125541.
18. Leung K.M.Y. *, Yeung K.W.Y., You J., Choi K., Zhang X.-W., Smith R., Zhou G., Yung M.M.N., Arias-Barreiro C., An Y.-J., Burket S.R., Dwyer R., Goodkin N., Hii Y.S., Hoang T., Humphrey C., Iwai C.B., Jeong S.-W., Juhel G., Karami A., Kyriazi-Huber K., Lee K.-C., Lin B., Lu B., Martin P., Nillos M.G., Oginawati K., Rathnayake V., Risjani Y., Shoeb M., Tan C.H., Tsuchiya M.C., Ankley G.T., Boxall A.B.A., Rudd M.A., Brooks B.W., Towards sustainable environmental quality: Priority research questions for Asia, Environmental Toxicology and Chemistry, 2020, 39, 1485-1505
19. Liu G., Jiang R.-F.*, You J., Muir D., Zeng E.Y. Microplastic impacts on microalgae growth: Effects of size and humic acid. Environmental Science & Technology. 2020. 54, 1782-1789.
20. Ma P., Li H.-Z.*, You J. Full life-cycle toxicity assessment of sediment-bound DDT and its degradation products on Chironomus dilutus. Environmental Toxicology and Chemistry, 2019, 38, 2698–2707.
21. Wang S.-H., Li H.-Z., You J.* Enantioselective degradation and bioaccumulation of sediment-associated fipronil in Lumbriculus variegatus: Toxicokinetic analysis. Science of the Total Environment, 2019, 672, 335–341.
22. Ma X., Li H.-Z., Xiong J.J., Mehler W.T., You J.* Developmental toxicity of a neonicotinoid insecticide, acetamiprid to zebrafish embryos, Journal of Agricultural and Food Chemistry, 2019, 67, 2429–2436.
23. Wang Z., Brooks B.W., Zeng E.Y., You J.* Comparative mammalian hazards of neonicotinoid insecticides among exposure durations, Environmental International, 2019, 125, 9–24.
24. Li H.-Z., Yi X.-Y., Cheng F., Tong Y.-J., Mehler W.T., You J.* Identifying organic toxicants in sediment using effect-directed analysis: a combination of bioaccessibility-based extraction and high-throughput midge toxicity testing, Environmental Science & Technology, 2019, 53, 996–1003.
25. Xiong J.J., Wang Z., Ma X., Li, H.-Z., You J.* Occurrence and risk of neonicotinoid insecticides in surface water in a rapidly developing region: Application of polar organic chemical integrative samplers, Science Total of Environment, 2019, 648, 1305–1312.
26. Zhang X.*, You J., Khim J.S.*, Wang T. Coastal ecosystem in East Asia: pollution and management. Environmental Pollution. 2019, 251, 990–992.
27. Li H.-Z., You J.*, Wang W.-X.*, Multi-compartmental toxicokinetic modeling of fipronil in tilapia: Accumulation, biotransformation and elimination. Journal of Hazardous Materials, 2018, 360, 420–427.
28. Li H.-Z., Zhang J., You J.* Diagnosis of complex mixture toxicity in sediment: Application of toxicity identification evaluation and effect-directed analysis. Environmental Pollution, 2018, 237, 944–954.
29. Mehler W. T., You J.*, Keough M. J., Lydy M. J., Pettigrove V. Improvements and cost-effective measures to the automated intermittent water renewal system for toxicity testing with sediments, Ecotoxicology and Environmental Safety, 2018, 151, 62–67.
30. Xiong J.-J., Li H.-Z., Ma X., You J. *, Synthesis and application of a novel solid-phase extraction adsorbent for multiresidue analysis of insecticides in water. Journal of Separation Science, 2018, 41, 525–533.
31. Zhang J., You J., Li H.-Z.*, Mehler W.T., Zeng E.Y. Particle-scale understanding of cypermethrin in sediment: Desorption, bioavailability, and bioaccumulation in benthic invertebrate Lumbriculus variegatus, Science Total of the Environment, 2018, 642, 638–645.
32. Zhang J.-R., Li H.-Z.*, Zhou Y.-Z., Dou L., Cai L.-M., Mo L.-P., You J., Bioavailability and soil-to-crop transfer of heavy metals in farmland soils: A case study in the Pearl River Delta, South China, Environmental Pollution, 2018, 235, 710–719.
33. Jiang R.-F., Lin W., Wu J.-Y. , Xiong Y.-X., Zhu F., Bao L.-J., You J., Ouyang G.-F.*, Zeng E.Y. Quantifying nanoplastic-bound chemicals accumulated in Daphnia Magna with a passive dosing method, Environmental Science: Nano., 2018, 5, 776–781.
34. Pan S.-X., Lin L.-F., Zeng F., Zhang J.-P., Dong G.-H., Yang B.-Y., You J., Chen S.-J., Zhang G., Yu Z.-Q., Sheng G.-Y., Ma H.-M.*, Effects of lead, cadmium, arsenic, and mercury co-exposure on children's intelligence quotient in an industrialized area of southern China, Environmental Pollution, 2018, 235, 47–54.
35. You J., Li H.-Z.*. Improving the accuracy of effect-directed analysis: The role of bioavailability, Environmental Science: Processes & Impacts, 2017, 19, 1484–1498 (cover).
36. Zhang J.-J., Wei Y.-L., Li H.-Z., Zeng E.Y., You J.* Application of Box-Behnken design to optimize multi-sorbent solid phase extraction for trace neonicotinoids in water containing high level of matrix substances. Talanta, 2017, 170, 392–398.
37. Li H.-Z., Cheng F., Wei Y.-L., Lydy M. J., You J.* Global occurrence of pyrethroid insecticides in sediment and the associated toxicological effects on benthic invertebrates: An overview. Journal of Hazardous Materials, 2017, 324, 258–271.
38. Pei Y.-Y., Halbrook S. R., Li H.-Z., You J.* Homing pigeons as a biomonitor for atmospheric PAHs and PCBs in Guangzhou, a megacity in South China. Marine Pollution Bulletin, 2017, 124, 1048–1054.
39. Li H.-Z., Wang F., You J.* Bioaccumulation of sediment-bound dichlorodiphenyltrichloroethane and heavy metals in benthic polychaete, Nereis succinea from a typical mariculture zone in South China. Marine Pollution Bulletin, 2017, 124, 1040–1047.
40. Pei Y.-Y., Li H.-Z., You J.* Determining equilibrium partition coefficients between lipid/protein and polydimethylsiloxane for highly hydrophobic organic contaminants using preloaded disks, Science of the Total Environment, 2017, 598, 385–392.
41. Wei Y.-L., Li H.-Z., Zhang J.-J., Xiong J.-J., Yi X.-Y., You J.* Legacy and current-use insecticides in agricultural sediments from South China: Impact of application pattern on occurrence and risk. Journal of Agricultural and Food Chemistry, 2017, 65, 4247–4254.
42. Qi H.-X., Li H.-Z., Wei Y.-L., Mehler W.T., Zeng E.Y., You J.*, Effect-directed analysis of toxicants in sediment with combined passive dosing and in vivo toxicity testing. Environmental Science & Technology, 2017, 51, 6414–6421.
43. Cheng F., Li H.-Z.*, Qi H.-X., Han Q., You J., Contribution of pyrethroids in large rivers to sediment toxicity assessed with benthic invertebrate Chironomus dilutus: A case study in South China, Environmental Toxicology and Chemistry, 2017, 36, 3367–3375
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44. Lohmann R.*, Muir D., Zeng E.Y., Bao L.-J., Allan I., Arinaitwe K., Booij K., Helm P., Kaserzon S., Mueller J., Shibata Y. Smedes F. Tsapakis M., Wong C., You J. Aquatic global passive sampling (AQUA-GAPS) revisited: First steps towards a network of networks for organic contaminants in the aquatic environment, Environmental Science & Technology, 2017, 51,1060–106
.45. 裴媛媛，佟宇俊，李慧珍，符志友，张远，游静*, 基于原位生物测试的水生态风险评估技术研究, 环境科学研究, 2020, 33, 2437–2447
46. 王顺慧, 李慧珍, 游静*. 利用毒代动力学模型研究氟虫腈在夹杂带丝蚓体内的手性选择性积累过程, 环境化学, 2020, 39, 156–165 (封面).
47. 李慧珍，裴媛媛，游静*. 流域水环境复合污染生态风险评估的研究进展. 科学通报, 2019, 64, 3412-3428.
48. 熊晶晶, 李慧珍, 马雪, 张杰, 游静*. 极性有机物整合采样技术在监测水环境中农药的应用, 生态毒理学报, 2017, 12, 2–14.
49. 马萍, 程飞, 李慧珍, 游静*, 聚二甲基硅氧烷被动加标法在水毒性测试中的应用: 现状与进展, 环境化学, 2017, 36, 1177–1188 (封面)
50. 张俊杰, 韦燕莉, 李慧珍, 游静*, 水体中新烟碱类杀虫剂的固相萃取方法优化: 响应曲面法, 环境化学, 2017, 36, 1064–1071.
51. 廖春阳, 鲍恋君, 崔欣毅, 游静* 有机污染物生物有效性研究的方法与应用, 环境化学前沿（第二辑） 江桂斌, 郑明辉, 孙红文, 蔡勇编, 2017, pp. 47-67
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2021.04-2023.03广州市民生项目，基于原位效应和数据挖掘的广州市水污染监测及防控技术集成, 执行中（项目负责人）
2020.01-2023.12U1901220，国家自然科学基金委-广东省联合基金重点项目，大湾区河口典型有机污染特征及基于多证据链的生态效应，执行中（项目负责人）
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2020.01-2023.1241977343 国家自然科学基金面上项目，基于有害结局路径导向分析的城市水体沉积物毒性鉴别评价，执行中（项目负责人）
2019.01-2021.12比利时Firmenich（法国Oreal公司）合作项目，Investigations on alternatives to fish acute toxicity tests, involving the Chinese fish species for China notifications，执行中（课题负责人）
2018.01-2021.1241773101 国家自然科学基金面上项目，农业区水-沉积物体系中常见杀虫剂的迁移降解行为及其对沉积物毒性的影响机制，执行中（课题负责人）
2016.01-2021.062016A030312009 广东省自然科学基金团队项目，作物吸收累积邻苯二甲酸酯的基因型差异及其机理研究，执行中（核心成员）
2020.01-2023.1221976068 国家自然科学基金面上项目，离子型化合物在斑马鱼不同发育阶段的分配行为和预测研究，执行中（负责人：Bryan Brooks，广东省高等学校珠江学者讲座教授）
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2020.10-2022.52020M68392 中国博士后科学基金面上资助，城市室内宠物毛发对人体健康风险的集成评价策略，执行中 （负责人：程飞，博士后）
2021.01-2022.1242007366 国家自然科学基金青年基金项目，基于混合吸附剂被动采样及斑马鱼胚胎测试的效应导向分析：致毒物筛查中离子型化合物的毒性贡献，执行中（负责人：熊晶晶，博士后）
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2017.01-2020.122017ZX07301-005-002 国家重大科技项目水体污染控制与治理科技重大专项子课题，流域水环境风险管理技术集成-流域水环境复合污染生态风险评估技术体，结题中（子课题负责人）
2017.01-2019.122017A020216002 广东省省级科技计划项目，结合水体被动采样的效应导向分析方法的建立与应用，结题（课题负责人）
2016.07-2019.062015TX01Z168 广东省科技创新领军人才项目，环境监测与环境风险评价技术，结题（课题负责人）
2015.01-2018.1241473106，国家自然科学基金面上项目，被动采样在珠三角典型城市水体沉积物毒性评价中的应用：常见农药体内代谢分配的影响，结题（课题负责人）
2013.01-2016.1241273120，国家自然科学基金面上项目，珠江广州段水体沉积物生态毒性的鉴别与评价，结题（课题负责人）
2013.01-2015.1241222024，国家自然科学基金优秀青年基金项目，环境地球化学，结题（课题负责人）
2010.01-2012.1240971263，国家自然科学基金面上项目，沉积物中超级吸附剂及生物扰动对疏水性有机污染物的生物有效性和生物积累的影响，结题（课题负责人）
环境污染与健康团队